Binary systems are pretty good at understanding 0s and 1s.....dont worry about fluctations, they are a phonemenon of the pipeline where binary signal synchronize....or specific operaions cause a phenomenon in electrical pull inside the pipeline....if you actually stare at your system, you will see that the fluctuatuions are not totally random.....
It depends on the operation, pipeline complexity, stages....etc...
Basically, if its in a +/- 1volt range of the set voltage, you should be fine....