[Rawmaterial]

I've ran house call, sophos, ad-aware, spy-bot, still can't get these pop ups away.

Logfile of HijackThis v1.99.1
Scan saved at 10:34:45 AM, on 9/23/2007
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v7.00 (7.00.5730.0011)

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\Intel\Wireless\Bin\EvtEng.exe
C:\Program Files\Intel\Wireless\Bin\S24EvMon.exe
C:\Program Files\Intel\Wireless\Bin\WLKeeper.exe
C:\WINDOWS\system32\spoolsv.exe
C:\Program Files\Dell\NICCONFIGSVC\NICCONFIGSVC.exe
C:\Program Files\Intel\Wireless\Bin\RegSrvc.exe
C:\Program Files\Sophos\Sophos Anti-Virus\SAVAdminService.exe
C:\Program Files\Sophos\Remote Management System\ManagementAgentNT.exe
C:\Program Files\Sophos\AutoUpdate\ALsvc.exe
C:\Program Files\Sophos\Remote Management System\RouterNT.exe
C:\WINDOWS\system32\Ati2evxx.exe
C:\WINDOWS\Explorer.EXE
C:\Program Files\Apoint\Apoint.exe
C:\Program Files\Apoint\Apntex.exe
C:\WINDOWS\system32\ctfmon.exe
C:\Program Files\Sophos\AutoUpdate\ALMon.exe
C:\Program Files\HijackThis\HijackThis.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = Live Search
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = Live Search
O4 - HKLM\..\Run: [Apoint] C:\Program Files\Apoint\Apoint.exe
O4 - HKLM\..\Run: [SearchIndexer] rundll32.exe "C:\WINDOWS\system32\wlamlhai.dll",sitypnow
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - Global Startup: AutoUpdate Monitor.lnk = C:\Program Files\Sophos\AutoUpdate\ALMon.exe
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_02\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_02\bin\ssv.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: AIM - {AC9E2541-2814-11d5-BC6D-00B0D0A1DE45} - C:\PROGRA~1\AIM\aim.exe
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O11 - Options group: [INTERNATIONAL] International*
O16 - DPF: {0EB0E74A-2A76-4AB3-A7FB-9BD8C29F7F75} (CKAVWebScan Object) - http://www.kaspersky.com/kos/english...an_unicode.cab
O16 - DPF: {1EF9F042-C2EB-4293-8213-474CAEEF531D} (TmHcmsX Control) - http://www.trendsecure.com/framework...ex/TmHcmsX.CAB
O20 - AppInit_DLLs: C:\PROGRA~1\Sophos\SOPHOS~1\detoured.dll
O21 - SSODL: WPDShServiceObj - {AAA288BA-9A4C-45B0-95D7-94D524869DB5} - C:\WINDOWS\system32\WPDShServiceObj.dll
O23 - Service: Ati HotKey Poller - Unknown owner - C:\WINDOWS\system32\Ati2evxx.exe
O23 - Service: DomainService - Unknown owner - C:\WINDOWS\system32\ibclpwrm.exe (file missing)
O23 - Service: EvtEng - Intel Corporation - C:\Program Files\Intel\Wireless\Bin\EvtEng.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: iPod Service - Apple Inc. - C:\Program Files\iPod\bin\iPodService.exe
O23 - Service: NICCONFIGSVC - Dell Inc. - C:\Program Files\Dell\NICCONFIGSVC\NICCONFIGSVC.exe
O23 - Service: RegSrvc - Intel Corporation - C:\Program Files\Intel\Wireless\Bin\RegSrvc.exe
O23 - Service: Spectrum24 Event Monitor (S24EventMonitor) - Intel Corporation - C:\Program Files\Intel\Wireless\Bin\S24EvMon.exe
O23 - Service: Sophos Anti-Virus status reporter (SAVAdminService) - Sophos Plc - C:\Program Files\Sophos\Sophos Anti-Virus\SAVAdminService.exe
O23 - Service: Sophos Anti-Virus (SAVService) - Sophos Plc - C:\Program Files\Sophos\Sophos Anti-Virus\SavService.exe
O23 - Service: Sophos Agent - Unknown owner - C:\Program Files\Sophos\Remote Management System\ManagementAgentNT.exe" -service -name Agent (file missing)
O23 - Service: Sophos AutoUpdate Service - Sophos Plc - C:\Program Files\Sophos\AutoUpdate\ALsvc.exe
O23 - Service: Sophos Message Router - Unknown owner - C:\Program Files\Sophos\Remote Management System\RouterNT.exe" -service -name Router -ORBListenEndpoints iiop://:8193/ssl_port=8194 (file missing)
O23 - Service: WLANKEEPER - Intel® Corporation - C:\Program Files\Intel\Wireless\Bin\WLKeeper.exe

[Osiris]

what popups are you getting? post some screenshots