I can't speak for the Mactels (Mac Pro, Mac Book, most models released since January, 2006), however, the PowerMacs, starting with the G3 family, are 90% "standards" compliant - they use off the shelf RAM, harddrives, and CD drives (albeit with special patches on the last) - the exception was the video card; it required a special firmware. So yes, you could get a Mac Pro, pop some more RAM in it, manually upgrade the harddrives, but I don't know about the videocard.