well, whats on the drive that you can move? installed programs you cannot for obvious reasons, but files such as documents or images or whatever else may find a home on the c: can be moved to another partition.
for example, on my setup i have 2 hd's. one is 80gb that s split into 4 partitions, the other is 120gb, split into three. all i have on my main c: is 8gb set aside for the os, and whatever programs i install onto it. other than that, anything else i have on my pc resides on a partition, such as one for games, mp3's, files, my website etc ...