Well your post is kinda hard to understand. Why do you need an AMD optimizer? Have you checked your Temps? Install a program to see what your temps are. Also make sure your CPU heat sink are seated properly.
Did vista install good any hitches during install? Uninstall the optimizer and find a program to clean up your registry. If you cant find any way to check your temps as soon as it locks up shut down and look at temps in your BIOS.