Don't touch the PCI-e settings, unless you know what you're doing. Set the ram timings to manufacturers specifications. I think yours is like 4-4-4-15. I could be wrong, so check to make sure. Leave the multiplier where it is. Then just up the FSB, in small increments. Then test for stability. Use programs like Prime95 or Orthos. A good stabiliy run is 8-24hrs. So run it overnight when you sleep. If it's stable, up the FSB more. If it's not stable, you probably have to up the voltage on the VCore (CPU). But don't go to high. I'm not sure of the safe voltages for Pentium Ds. I think 1.2v-1.4v...