Ok, i've got avast! running in the background, i've got it doing a thorough scan on the drive with the problems. I'll run the other software afterwards.
Here's what the Hijack this log give me.
Logfile of HijackThis v1.99.1
Scan saved at 14:05:45, on 09/02/2007
Platform: Windows XP SP2 (WinNT 5.01.2600)
MSIE: Internet Explorer v6.00 SP2 (6.00.2900.2180)
Running processes:
E:\WINDOWS\System32\smss.exe
E:\WINDOWS\system32\winlogon.exe
E:\WINDOWS\system32\services.exe
E:\WINDOWS\system32\lsass.exe
E:\WINDOWS\system32\Ati2evxx.exe
E:\WINDOWS\system32\svchost.exe
E:\WINDOWS\System32\svchost.exe
E:\WINDOWS\system32\Ati2evxx.exe
E:\WINDOWS\system32\spoolsv.exe
E:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
E:\Program Files\Alwil Software\Avast4\ashServ.exe
E:\WINDOWS\System32\svchost.exe
E:\WINDOWS\system32\svchost.exe
E:\Program Files\Alwil Software\Avast4\ashMaiSv.exe
E:\Program Files\Alwil Software\Avast4\ashWebSv.exe
E:\Program Files\Zune\ZuneLauncher.exe
E:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
E:\Program Files\MSN Messenger\MsnMsgr.Exe
E:\Program Files\ATI Technologies\ATI.ACE\CLI.EXE
E:\Program Files\Steam\Steam.exe
E:\Program Files\ATI Technologies\ATI.ACE\cli.exe
E:\Program Files\ATI Technologies\ATI.ACE\cli.exe
E:\Program Files\Xfire\Xfire.exe
E:\Program Files\MSN Messenger\usnsvc.exe
E:\WINDOWS\explorer.exe
E:\Program Files\Alwil Software\Avast4\ashSimpl.exe
E:\Documents and Settings\Scott\Desktop\hijackthis\HijackThis.exe
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O4 - HKLM\..\Run: [ATICCC] "E:\Program Files\ATI Technologies\ATI.ACE\CLIStart.exe"
O4 - HKLM\..\Run: [Zune Launcher] "E:\Program Files\Zune\ZuneLauncher.exe"
O4 - HKLM\..\Run: [avast!] E:\PROGRA~1\ALWILS~1\Avast4\ashDisp.exe
O4 - HKCU\..\Run: [MsnMsgr] "E:\Program Files\MSN Messenger\MsnMsgr.Exe" /background
O4 - HKCU\..\Run: [Steam] "E:\Program Files\Steam\Steam.exe" -silent
O4 - Startup: Xfire.lnk = E:\Program Files\Xfire\xfire.exe
O9 - Extra button: (no name) - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra 'Tools' menuitem: @xpsp3res.dll,-20001 - {e2e2dd38-d088-4134-82b7-f2ba38496583} - %windir%\Network Diagnostic\xpnetdiag.exe (file missing)
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - E:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - E:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {48884C41-EFAC-433D-958A-9FADAC41408E} (EGamesPlugin Class) -
https://www.e-games.com.my/com/EGamesPlugin.cab
O16 - DPF: {D1E7CBDA-E60E-4970-A01C-37301EF7BF98} (Measurement Services Client v.3.11) -
http://gameadvisor.futuremark.com/global/msc311.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{BA795CE7-E1EE-459F-9D60-085CDAAC6AE2}: NameServer = 62.31.144.39,195.188.53.175
O18 - Protocol: livecall - {828030A1-22C1-4009-854F-8E305202313F} - E:\PROGRA~1\MSNMES~1\MSGRAP~1.DLL
O18 - Protocol: msnim - {828030A1-22C1-4009-854F-8E305202313F} - E:\PROGRA~1\MSNMES~1\MSGRAP~1.DLL
O21 - SSODL: WPDShServiceObj - {AAA288BA-9A4C-45B0-95D7-94D524869DB5} - E:\WINDOWS\system32\WPDShServiceObj.dll
O23 - Service: avast! iAVS4 Control Service (aswUpdSv) - Unknown owner - E:\Program Files\Alwil Software\Avast4\aswUpdSv.exe
O23 - Service: Ati HotKey Poller - ATI Technologies Inc. - E:\WINDOWS\system32\Ati2evxx.exe
O23 - Service: ATI Smart - Unknown owner - E:\WINDOWS\system32\ati2sgag.exe
O23 - Service: avast! Antivirus - Unknown owner - E:\Program Files\Alwil Software\Avast4\ashServ.exe
O23 - Service: avast! Mail Scanner - Unknown owner - E:\Program Files\Alwil Software\Avast4\ashMaiSv.exe" /service (file missing)
O23 - Service: avast! Web Scanner - Unknown owner - E:\Program Files\Alwil Software\Avast4\ashWebSv.exe" /service (file missing)